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Geisinger Medical Laboratories Test Catalog
MYELOPEROXIDASE ANTIBODY |
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Geisinger Epic Procedure Code: LAB2730
Geisinger Epic ID: 17737
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SPECIMEN COLLECTION |
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Specimen type: |
Serum | |
Preferred collection container: |
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Alternate Collection Container: |
6 mL red-top (plain, non-serum separator) tube
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Specimen required: |
0.5 mL serum; minimum 0.2 mL | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Allow to clot. Centrifuge and submit 0.5 mL serum. | |
Transport temperature: |
Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable. | |
Specimen stability: |
Room temperature: 8 hours. 2-8°C: 48 hours. Frozen: 6 months. | |
Rejection criteria: |
Specimen stability exceeded; specimen grossly hemolyzed. | |
TEST DETAILS |
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Reference interval: |
Negative <3.5 U/mL | |
Interpretation guide: |
Negative <3.5 U/mL Equivocal 3.5- 5.0 U/mL Positive >5.0 U/mL |
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CPT code(s): |
86037 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
Antibody detection to myeloperoxidase (MPO). | |
Methodology: |
Enzyme Immunoassay (EIA) |
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Synonyms: |
ANTI-MYELOPEROXIDASE AB, ANTI-MYELOPEROXIDASE ANTIBODY p-ANCA, ANTI-MPO, MPO
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Clinical significance: |
Anti-MPO antibodies are highly specific for idiopathic and vasculitis-associated crescentic glomerulonephritis and also for classic polyarteritis nodosa, Churg-Strauss syndrome, and polyangitis overlap syndrome. The presence of anti-MPO antibodies is also used in conjunction with other clinical tests to aid in the diagnosis of inflammatory bowel disease. | |
Doctoral Director(s:) |
Hoi-Ying Elsie Yu PhD, DABCC, FADLM | |
| Review Date: | 12/13/2022 | |