Geisinger Medical Laboratories Test Catalog

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FISH FOR BCR ABL

SPECIMEN COLLECTION
Test code:
BCRAB
Specimen type:
Bone marrow (preferred) or whole blood.
Preferred collection container:
Specimen Required:
3 mL (minimum 1 mL) bone marrow in culture transport medium or sodium heparin tube (preferred). Whole blood (minimum 2-3 mL) in sodium heparin tube also acceptable.
Special notes:
Clinical history and reason for referral are required with test order. Prior therapy and bone marrow transplant history should be provided with test order.

SPECIMEN PROCESSING
Transport temperature:
Room temperature.
Rejection criteria:
Frozen specimens unacceptable.

TEST DETAILS
Reference interval:
Interpretive report.
Additional information:
This test is performed to detect the molecular rearrangement of the bcr and abl genes involved in translocation 9,22, associated with chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL), using FISH (fluorescence in situ hybridization). This test may be used in the evaluation of pH negative CML, complex rearrangements or for follow-up to therapy for previously diagnosed Ph+ patients. If one or more fluorescence in situ hybridization (FISH) tests are ordered on a specimen without chromosome analysis, Test Code 14256 (CPT 88237) will be charged for tissue culture. If results are not possible, the test order may be canceled and replaced by code 416 - Cytogenetics Communication. Bone marrow transport medium is available upon request.
CPT code(s):
88271 x2, 88275
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
FISH, CML/ALL, BCR/ABL Translocation 9,22
Synonyms:
Fish for BCR/ABL t(9;22) Rearrangement
FISH, CML/ALL, BCR/ABL Translocation 9,22

Performing Locations

Quest Diagnostics
Technical Lead: Michael Weaver    
Frequency: Monday-Sunday morning    
Performed stat? N
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