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Geisinger Medical Laboratories Test Catalog
ENDOMYSIAL ANTIBODY SCREEN (IGA), REFLEX TO TITER |
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Geisinger Epic Procedure Code: LAB2216
Geisinger Epic ID: 45693
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SPECIMEN COLLECTION |
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Specimen type: |
Serum | |
Preferred collection container: |
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Alternate Collection Container: |
6 mL red-top (plain, non-serum separator) tube
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Specimen required: |
1 mL serum; minimum 0.3 mL | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Centrifuge and aliquot | |
Transport temperature: |
Refrigerated. | |
Specimen stability: |
Room temperature: 7 days. Refrigerated: 21 days. Frozen: 21 days. | |
TEST DETAILS |
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Additional information: |
If Endomysial Antibody (IgA) Screen is abnormal, Endomysial Antibody Titer will be performed at an additional charge (CPT code(s): 86256). | |
CPT code(s): |
86231 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Methodology: |
Immunofluorescence Assay |
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Synonyms: |
Quest test code 15064 ENDOAB
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Clinical significance: |
The presence of anti-endomysial (EMA) IgA antibodies has been shown to correlate with gluten-sensitive enteropathy such as celiac disease (CD) and dermatitis herpetiformis (DH). EMA is detected primarily by IFA, using monkey esophagus as a substrate and observing fluorescence of the endomysial lining. Patients with CD and DH can also demonstrate antibodies to reticulin and gliadin, though EMA-IgA seems to be the most specific marker (specifically 94-100%). | |