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Geisinger Medical Laboratories Test Catalog
COMPLEMENT, TOTAL (CH50) |
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Geisinger Epic Procedure Code: LAB1976
Geisinger Epic ID: 27128
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SPECIMEN COLLECTION |
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Specimen type: |
Serum | |
Preferred collection container: |
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Alternate Collection Container: |
6 mL red-top (plain, non-serum separator) tube
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Specimen required: |
1 mL aliquot of serum; minimum 0.5 mL. Please submit a separate frozen aliquot for this test. It may not be combined with any other test requiring a frozen aliquot. | |
Special notes: |
Please note: CSF, Pleural Fluid, Pericardial Fluid, and Synovial Fluid are unacceptable for this test. Do not submit the sample in a glass tube. | |
Patient preparation: |
Fasting specimen preferred. | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Allow to clot. Centrifuge serum specimens within 1 hour of collection. Immediately pipette serum into sterile, plastic, screw-capped vial(s) and freeze solid -20 degrees C or lower. Do not allow samples to thaw. With multiple tests, submit a separate tube for each test. Refrigerated specimens and those at room temperature are not acceptable. | |
Transport temperature: |
Frozen. | |
Specimen stability: |
Room Temperature: Unacceptable. Refrigerated: Unacceptable. Frozen: 30 days. |
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Rejection criteria: |
CSF, Pleural Fluid, Pericardial Fluid, and Synovial Fluid are unacceptable. Specimens that are not frozen are unacceptable. Gross hemolysis. Lipemia. | |
TEST DETAILS |
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Reference interval: |
31-60 U/mL. Detection limit 10 U/mL | |
Additional information: |
CH50 values below the reference range may indicate a deficiency in one or more of the components of complement. To obtain more definitive information, abnormal specimens should be assayed for levels of the individual components (C1 to C9). Elevated values of CH50 are associated with inflammation or infection. Reduced values may result from consumption of complement by immune complexes or a hereditary deficiency of a complement component. Patients with certain rheumatic diseases, especially with active SLE, may have a low total complement level. Because some complement components are unstable during processing, shipment, or storage, it is prudent to confirm an unexpectedly low value of CH50 by repeating the test on a new sample. | |
CPT code(s): |
86162 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
Complement total CH 50 | |
Methodology: |
Liposome |
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Synonyms: |
COMPLEMENT, TOTAL CH50, TCH50 Quest test code 618
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