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Geisinger Medical Laboratories Test Catalog
SERUM PROTEIN ELECTROPHORESIS REFLEX PROFILE |
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Geisinger Epic Procedure Code: LAB3052
Geisinger Epic ID: 32246
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SPECIMEN COLLECTION |
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Specimen type: |
Serum | ||||||||||||||
Preferred collection container: |
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Alternate Collection Container: |
6 mL red-top (plain, non-serum separator) tube
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Specimen required: |
1 mL serum; minimum 0.5 mL | ||||||||||||||
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Allow to clot. Centrifuge and submit 1 mL of serum. | ||||||||||||||
Transport temperature: |
Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable. | ||||||||||||||
Specimen stability: |
Room temperature: 8 hours. 2-8°C: 4 days. Frozen: Unlimited. | ||||||||||||||
Rejection criteria: |
Specimen stability exceeded; specimen grossly hemolyzed. | ||||||||||||||
TEST DETAILS |
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Reference interval: |
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CPT code(s): |
84165 | ||||||||||||||
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | |||||||||||||||
Test includes: |
Total protein and serum electrophoresis with interpretation. Based on pathologist review, testing may reflex to Serum Immunofixation (IFES), Immunoglobulin Quantitation (GAM) and/or Kappa/Lambda Ratio at an additional charge. | ||||||||||||||
Methodology: |
Electrophoresis |
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Synonyms: |
SPEP, Serum Protein Electrophoresis (SPE) EPGSP
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Clinical significance: |
Serum protein electrophoresis evaluates 5 major protein fractions (albumin, alpha 1, alplha 2, beta and gamma) in serum to determine if there are deficiencies or increases that can have association with diseases such as macroglobulinemia, monoclonal gammopathy of undetermined significance (MGUS) or multiple myeloma. | ||||||||||||||
Doctoral Director(s:) |
Hoi-Ying Elsie Yu PhD, DABCC, FADLM | ||||||||||||||
| Review Date: | 06/15/2023 | ||||||||||||||