Dr. Hoi-Ying (Elsie) Yu
HOI-YING (ELSIE) YU, Ph.D, DABCC, FADLM
System Director, Chemistry, Point-of-Care Testing and Preanalytics
Director, Clinical Pathology Informatics
100 North Academy Avenue
Danville, PA 17822-1930
800-695-6491
Dr. Yu is an Associate of Geisinger Medical Laboratories at Geisinger Medical
Center, where she serves as the system director, Chemistry, Point-of-Care Testing and Preanalytics and the director of Clinical Pathology Informatics. She is also a member of the facult of the Geisinger Pathology Residency Program.
Education:
Dr. Yu received her Ph.D. in cellular and molecular biology at the University of Wisconsin-Madison, and completed a clinical chemistry fellowship at Children's Hospital Boston.
Professional Affiliations:
American Society for Clinical Pathology
International Association of Therapeutic Drug Monitoring & Clinical Toxicology
National Academy of Clinical Biochemistry
Association of Pathology Informatics
Canadian Society of Clinical Chemists
Association for Diagnostics & Laboratory Medicine
Research Interests:
Selected Honors and Awards
2016 ASCP 40 under Forty Top Five Honoree, American Society for Clinical Pathology, August 2016, in recognition of outstanding laboratory leadership and contribution among laboratory professionals under the age of 40.
AACC’s Outstanding Speaker Award, American Association of Clinical Chemistry, June 2016, in recognition of outstanding contributions to continuing education in 2015.
AACC’s Outstanding Speaker Award, American Association of Clinical Chemistry, April 2015, in recognition of outstanding contributions to continuing education in 2014.
AACC’s Outstanding Speaker Award, American Association of Clinical Chemistry, April 2014, in recognition of outstanding contributions to continuing education in 2013.
SYCL Travel Award, American Association of Clinical Chemistry, July 2011, in support of travel to the AACC Annual Meeting.
Career Development Program Fellow Award, The Leukemia & Lymphoma Society, July 2008, in support of postdoctoral training.
Online Courses
Yu HE. AACC Learning Lab – Course Author / Developer for “Pharmacogenetics" - Sept 2015. https://www.aacc.org/lp/learning-lab
Yu HE. Pharmacogenetics for Drug Hypersensitivity Reactions. AACC Pearls of Laboratory Medicine. 2016. DOI: 10.15428/CCTC.2015.252858.
Interviewed articles
CAP TODAY. December 2023. “Savings follow allergy, autoimmune test consolidation”.
Today’s Clinical Lab. 2023. “The Power of Vendor – Laboratory Partnerships”. https://www.clinicallab.com/the-power-of-vendor-laboratory-partnerships-27587
Roche LabLeaders. 2021. “How to Build Your Multidisciplinary Implementation Team”.
Roche Diagnostic case study. 2019. “How Geisinger Health Used a Five-Step Strategy to Implement High-Sensitive Troponin Testing”.
Roche Diagnostic case study. 2018. “Geisinger Medical Center Transforms their Laboratory with a State-of-the-art Total Automation System”.
CAP Today. November 2017. “Next-gen troponin: out of the gate, into labs”
Publications in Peer-Reviewed Journals:
Lo S-Y, Yu HE. Moving average for a qualitative assay: an experiment with anti-hepatitis B core antibody serology testing. J Appl Lab Med. 2023; In: press.
Shepherd J, Whetstone M, Mertz BJ, Lo S-Y, Yu HE. Uncommon Water Contaminant That Impacts Triglyceride Test. J Appl Lab Med. 2023; 8: 843-845.
Nichols JH, Ali M, Anetor J, Chen LS, Chen Y, Collins S, Das S, Devaraj S, Fu L, Greene DN, Karon BS, Kary H, Nerenz R, Rai A, Shajani-Yi Z, Thakur V, Wang S, Yu HE, Zamora LE. AACC Guidance Document on the Use of Point-of-Care Testing in Fertility and Reproduction. J Appl Lab Med. 2022; 7: 1202-1236.
Khan A, Saleem M, Willner KD, Sullivan L, Yu HE, Mahmoud O, Alsaid A, Matsumura ME. Association of Chest Pain Protocol-Discordant Discharge with Outcomes Among Emergency Department Patients with Modest Elevations of High-Sensitivity Troponin. JAMA Network Open. 2022; 5(8): e2226809.
Miller WG, Kaufman HW, Levey AS, Straseski JA, Wilhelms KW, Yu HE, Klutts JS, Hilborne LH, Horowitz GL, Lieske J, Ennis JL, Bowling JL, Jewis MJ, Montgomery E, Vassalotti, JA, Inker LA. National Kidney Foundation Laboratory Engagement Working Group Recommendations for Implementing the CKD-EPI 2021 Race-Free Equations for Estimated Glomerular Filtration Rate: Practical Guidance for Clinical Laboratories. Clin Chem. 2022; 68: 511-520.
Yu HE, Lanzoni H, Steffen T, Derr W, Cannon K, Contreras J & Olson JE. Improving laboratory processes with total laboratory automation. Lab Med. 2019; 50: 96-102.
Yu HE & Wilkerson M. Employee engagement is vital for the successful selection of a total laboratory automation system. Lab Med. 2017; 48: e66-74.
Yu HE. The prescription drug abuse epidemic. Clin Lab Med. 2012; 32: 361-377.
Yu HE, Hawash K, Picker J, Stoler J, Urion D, Wu BL, Shen Y . A recurrent 1.71Mb genomic imbalance at 2q13 increases the risk of developmental delay and dysmorphism. Clin Genet. 2012; 81: 257-264.
Yu HE, Agus M, Kellogg MD. Clinical utility of Abbott Precision Xceed Pro ketone meter in diabetic patients. Pediatric Diabetes. 2011; 12: 649-655.
Yu HE, O’Brien JJ, Magnani B. Conflicting calcium concentrations in the presence of low albumin post bone marrow transplant. Clin Chem. 2010; 56: 1777.
Yu HE. Cyberintrusion – happening much closer to you than you might think. Clin Chem. 2010; 56: 1646-1647.
Woolf AD, Law T, Yu HE, Woolf N & Kellogg M. Lead poisoning from use of bronze drinking vessels during the late Chinese Shang dynasty: an in vitro experiment. Clin Tox. 2010; 48: 757-761.
Yu HE, Law T. Unexpectedly high TSH – another case of heterophile antibody. Clin Chem. 2010; 56: 1203.
Yu HE & Kellogg MD. Hyperkalemia or Hypokalemia. Clin Chem. 2010; 55: 2068.
Other Publications:
Yu HE. Point-of-Care Urinary Drug Screening. Clinical Toxicology News. 2021; An AACC/CAP Newsletter for Toxicology Laboratories: 9/2021, pages 1-4.
Yu HE. Bench Matters: Lab Standardization in the Era of Big Healthcare Networks. AACC Clin Lab News. 2017; 43(8): 4-5.
Yu HE. Ask the Expert: Pitfalls of Point-of-Care Urinary Drug Screening for Pain Management. AACC Clin Lab News. 2015; 41(7): 48.
Amarose E, Zook AK & Yu HE. Use of CoaguChek Device at a Pharmacist-Managed Warfarin Clinic. ASCLS Clinical Lab Investigations – Case Studies for the Laboratory Professional. 2013; Set13: Case 2.
Poster Presentations
Murphy J, Miller C, Hurst K, Yu HE. Enabling laboratories to do more with less: Assessment of workflow efficiencies through instrument consolidation in an Immunology lab. Poster presented at the 2023 American Association of Clinical Chemistry Annual Scientific Meetin, July 2023.
Mills J, Yu HE, Vanenkevort E, Hoffman S, Matsumura M and Voyce S. Concomitant Use of Creatine Kinase MB and High-sensitivity Troponin: What is the Cost?. Poster presented at the 2022 American Heart Association Annual Meeting, October 2022.
Laam L, Yu HE. Implementation of High-sensitivity Troponin Improve ED Discharge Time at Multiple Facilities in a Hospital System in Central Pennsylvania. Poster presented at the 2022 American Association of Clinical Chemistry Annual Meeting, July 2022.
Lo SY, Yu HE. Fine-Tuning Lipid Panel Reflex Testing Algorithm for Direct LDL Cholesterol Measurement. Poster presented at the 2019 American Association of Clinical Chemistry Annual Meeting, August 2019.
Yu HE, Olson J. Improving Laboratory Processes with Total Automation. Poster presented at the American Association of Clinical Chemistry Annual Meeting, August 2017.
Poler SM, Yu HE, Scholtis MP and Schieble TM. Comparison of Blood Glucose Determination from Earlobe Capillary Blood and Arterial Blood Specimens. Poster presented at the Society for Technology in Anesthesiology Annual Meeting, January 6-9, 2016.
Poler SM, Yu HE, Scholtis MP and Schieble TM. Comparison of Blood Glucose Determination from Earlobe Capillary Blood and Arterial Blood Specimens. Poster presented at the American Society of Anesthesiologists, October 24-28, 2015.
Sneidman MR, Yu HE. Performance comparison of Six Different Rapid Screening Drug Test Cards / Cups. Poster presented at the American Association of Clinical Chemistry Annual Meeting, July 26-30, 2015.
Sneidman MR, Yu HE. Comparison of Roche Methadone Screening Assay with DRI Methadone Metabolite (EDDP) Screening Assay. Poster presented at the 2014 American Association of Clinical Chemistry Annual Meeting, July 2014.
Amarose E, Farber LM, Soles DF, Yu HE. Performance of CardioChek in Lipid Testing of Health Screening Purposes. Poster presented at the 2012 American Association of Clinical Chemistry Annual Meeting,, July 16-19, 2012.
Jones JB, Young D, Smeal K, Kimmich D, Lopatka M, Sargent D, Nowak R, Yu HE, Kremitske D, Harrison HH. Integration of a Multisite Enterprise Quality Control Program on a Wide Area Network and Use of Sigma Statistics to Standardize Westgard QC Rules. Poster presented at the American Association for Clinical Chemistry Annual Meeting, July 16-19, 2012.
Yu HE, Agus M, Kellogg MD. Evaluation of Clinical Performance of Abbott Precision Xceed Pro Ketone Meter. Poster presented at the 2010 American Association of Clinical Chemistry Annual Meeting, July 2010.
Presentations and Invited Lectures
Yu HE. Access, Connect, and Engage (A.C.E.) - Keys to Future Success of Home Testing. Chaired and Presented at the 30th Molecular & Precision Med Tri-Conference, March 2023.
Yu HE. Premature Rupture of Membrane (PROM) testing, Fetal blood scalp (FBS) testing and umbilical cord blood testing: Clinical Utility and Performance. Presentation at the 2022 American Association of Clinical Chemistry Annual Meeting, July 2022.
Yu HE. AACC Guidance on the use of Point-of-Care Testing in Fertility and Reproduction. Presentation at the 2022 American Association of Clinical Chemistry Annual Meeting, July 2022.
Yu HE. Tips for more accessible, inclusive trainings. Presentation at the CDC’s OneLab Virtual Summit 2022, April 2022.
Yu HE. A glimpse into 2030 - Our future at-home testing model depends on now. Presentation at the Roche ASPIRE Point of Care webinar, April 2022.
Yu HE. At-Home Point-of-Care Testing – How Clinical Laboratory Professionals Can Assist. Chaired and presented at the 29th Molecular & Precision Med Tri-Conference, February 2022.
Yu HE. Elevating the value of at-home testing: what can we do now. Interactive discussion leader at the 29th Molecular & Precision Med Tri-Conference, February 2022.
Yu HE. Closing Care Gap in the Era of COVID – Laboratory Perspective. Presentation at the 28th Molecular Medicine TRI-CON Virtual Conference, February 2021.
Yu HE. Complexities of Laboratory Testing for Thyroid Dysfunction: When Hoofbeats are Actually Zebras. Presentation at the 2020 American Association of Clinical Chemistry Virtual Annual Meeting, December 2020.
Yu HE. Is Faster Always Better? Ensuring Quality and Proper Utilization of Point-of-Care Testing through Partnership. Presentation at the CDC ECHO (Extension for Community Healthcare Outcomes) session, September 2020.
Yu HE. Is Faster Always Better? Ensuring Quality and Proper Utilization of Point-of-Care Testing through Partnership. Chaired and presented at the 27th International Molecular Medicine Tri-Conference, March 2020.
Yu HE. Experience with Implementing a Rapid Intraoperative PTH Method at Geisinger Medical Center. Presentation at the 2019 American Association of Clinical Chemistry Annual Meeting,, August 2019.
Yu HE. How the Lab collaborates with Pharmacists and Clinicians to fight the Opioid Epidemic. Presentation at the 2019 American Association of Clinical Chemistry Annual Meeting,, May 2019.
Yu HE. How we use point-of-care testing to leverage the growing need of a multi-hospital health care system. Chaired and presented at the 26th International Molecular Medicine Tri-Conference, March 2019.
Yu HE. Gen. 5 TnT lessons learned. Presentation at the LabLeaders.com , January 2019.
Yu HE. How we Design and Operate our next-generation integrated Core Lab to streamline process and reduce waste. Presentation at the Solutions Powered by Roche, August 2018.
Yu HE. The Health System Growth Spurt: Ensuring uniform lab services across multiple hospitals and clinics. Presentation at the 2018 American Association of Clinical Chemistry Annual Meeting, July 2018.
Yu HE. Transforming Cardiac Care with Troponin T Generation 5: A multi-disciplinary Team’s Perspective. Presentation at the Roche Troponin T Gen 5 Advisory Group Webinar, June 2018.
Yu HE. Standardizing POCT Across Hospital and Health Systems. Chaired and presented at the 25th International Molecular Medicine Tri-Conference, February 2018.
Yu HE. Transforming Cardiac Care with Troponin T Generation 5: A Laboratory Perspective. Presentation at the Roche Milwaukee Troponin T Generation 5 workshop, November 2017.
Yu HE. Welcome to the Higher Standard: Transforming Cardiac Care with Next Generation Troponin T. Presentation at the 2017 Roche SmartLab Event, September 2017.
Yu HE. Strategy for Provider-Performed Microscopy Testing Competency Management. Presentation at the 2017 American Association of Clinical Chemistry Annual Meeting, July 2017.
Yu HE. Learning to Speak the Language of Procalcitonin – Geisinger Health System’s Strategy for Realizing the Full Clinical Utility of Procalcitonin. Webinar Series at the Compass Group, October 2016.
Yu HE. Pharmacogenetics for Drug Hypersensitivity Reactions. Presentation at the Canadian Laboratory Medicine Congress, June 2016.
Yu HE. The Inconvenient Truth about Near Patient Testing at the Doctor’s Office. Presentation at the Canadian Laboratory Medicine Congress, June 2016.
Yu HE. The Inconvenient Truth about Near Patient Testing at the Doctor’s Office. Presentation at the 23rd International Molecular Medicine Tri-Conference, March 2016.
Yu HE. The Inconvenient Truth about Near Patient Testing at the Doctor’s Office. Symposium: Chaired and presented at the the Point-of-Care Diagnostic Symposium, Part of the 23rd International Molecular Medicine Tri-Conference, March 10-11, 2016.
Yu HE. Selecting Automation / Instrumentation for Clinical Laboratory – it’s more than just finding the right technology. Presentation at the American Association of Clinical Chemistry Annual Meeting, July 26-30, 2015.
Yu HE. Decision Support for Urine Drug Testing for Pain Management. Presentation at the Canadian Laboratory Medicine Congress, June 20-24, 2015.
Yu HE. Selecting Automation / Instrumentation for Clinical Laboratory – it’s more than just finding the right technology. Presentation at the Canadian Laboratory Medicine Congress, June 20-24, 2015.
Yu HE. Decision Support for Urine Drug Testing for Pain Management. Presentation at the 2014 American Association of Clinical Chemistry Annual Meeting, July 2014.
Yu HE. Establish Partnership between Laboratory and Healthcare Providers to Improve Clinical Utility of Point-of-Care Testing. Presentation at the Third Annual Point-of-Care Diagnostic Symposium, Part of the 21st Annual Molecular Medicine Tri-Conference, February 13-14, 2014 .
Yu HE. Prescription Drug Compliance Monitoring: Decision Support for Test Ordering and Result Interpretation. Presentation at the 2013 American Association of Clinical Chemistry Annual Meeting, July 2013.
Yu HE. Establish Partnership between Laboratory and Healthcare Providers to Improve Clinical Utility of Point-of-Care Testing. Invited Talk at the Third Annual Point-of-Care Diagnostic Symposium, February 13-14. 2013.
Yu HE. Panel Discussion: Point-of-Care Implementation: Commercial, Health System, and Pharmacy Perspectives. Invited Talk at the Third Annual Point-of-Care Diagnostic Symposium, part of the 21st Annual Molecular Medicine Tri-Conference, February 13-14. 2013.
Textbooks and Book Chapters
Zucker ML, LaDuca FM, Owen R, Bennett SF, Clark S, Fantz CR, Halim AB, Kaur P, Khan A, Kocis PT, Lessard C, Nevins K, Riley PW, Stavelin A, Yu HE. Clinical and Laboratory Standards Institute Guideline POCT14—Point of Care Coagulation Testing and Anticoagulation Monitoring 2nd edition.Clinical and Laboratory Standards Institute, Wayne, PA , 2020.
Yu HE, Heger NE. Synthetic opioids In: Clinical Toxicology Testing: A Guide for Laboratory Professionals. Magnani BJ, Kwong T, McMillin G, Wu A, eds. CAP Press, Northfield, Illinois, 2020, 270-281.
Yu HE, Horowitz GL. Over-the-counter Aaalgesics In: Clinical Toxicology Testing: A Guide for Laboratory Professionals. Magnani BJ, Kwong T, McMillin G, Wu A, eds. CAP Press, Northfield, Illinois, 2020, 300-308.
Yu HE. Opioids 2: The Synthetic Opioids In: Clinical Toxicology Testing: A Guide for Laboratory Professionals. Magnani BJ, Bissell M, Kwong T, Wu A, eds. CAP Press, Northfield, IL, 2012, 149-156.
Yu HE, Magnani BJ. Over-the-counter Analgesics In: Clinical Toxicology Testing: A Guide for Laboratory Professionals. Magnani BJ, Bissell M, Kwong T, Wu A, eds. CAP Press, Northfield, IL, 2012, 179-187.
Yu HE, Magnani BJ . Acetaminophen and Salicylate In: The Clinical Toxicology Laboratory - Contemporary Practice of Poisoning Evaluation. Kwong TC, Magnani BJ, Rosano TG, Shaw LM, eds. AACC Press, Washington, DC, 2012, 189-202.