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Specimen Collection Manual and Test Catalog

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IGM

Geisinger Epic Procedure Code:  LAB2522    Geisinger Epic ID:  15029

SPECIMEN COLLECTION
Specimen type: 

Plasma or serum


Specimen required: 

1 mL of serum or plasma; minimum 0.2 mL.


Patient preparation: 

Fasting specimen preferred.



SPECIMEN PROCESSING
Processing instructions: 

Allow serum to clot. Centrifuge to separate serum or plasma within 2 hours of collection.


Transport temperature: 

Refrigerated (preferred). Room temperature or frozen specimen also acceptable.


Specimen stability: 

Room temperature: 2 months. Refrigerated: 4 months. Frozen: 6 months.


Rejection criteria: 

Stability limits exceeded.



TEST DETAILS
Reference interval: 

< 1 year: 0-145 mg/dL 
1 - < 4 years: 19-146 mg/dL 
4 - < 7 years: 24-210 mg/dL 
7 - <12 years: 31-208 mg/dL 
12 - <19 years: 35-239 mg/dL 
19 years and up: 40-230 mg/dL


CPT code(s):  82784
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

IgM quantitation.


Methodology: 
Immunoturbidity
Synonyms: 

Immunoglobulin M


Clinical significance: 

Increased IgM is associated with Waldenstrom's macroglobulinemia, infectious mononucleosis, viral infections, nephritic syndrome, and estrogen therapy. Decreased IgM is found in selective IgM deficiency, Bruton's disease and acquired immunodeficiency.


Doctoral Director(s): 
Hoi-Ying Elsie Yu, PhD, DABCC, FADLM
Sheng-Ying (Margaret) Lo, PhD, DABCC
Review Date:  12/27/2024

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