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Specimen Collection Manual and Test Catalog

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RUBEOLA (MEASLES) IGG ANTIBODY

Geisinger Epic Procedure Code:  LAB3026    Geisinger Epic ID:  7469

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
6 mL red-top (plain, non-serum separator) tube
Specimen required: 

0.5 mL serum; minimum 0.2 mL.



SPECIMEN PROCESSING
Processing instructions: 

Allow to clot. Centrifuge and submit 0.5 mL serum.


Transport temperature: 

Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable.


Specimen stability: 

Room temperature: 8 hours. 2-8°C: 7 days. Frozen: 6 months.


Rejection criteria: 

Specimen stability exceeded; specimen grossly hemolyzed.



TEST DETAILS
Interpretation guide: 
ResultInterpretation
NegativeAbsence of detectable measles virus IgG antibodies. A negative result generally indicates that the patient has not been infected and is susceptible to measles. If the subject has no history of measles, has not been previously vaccinated and exposure to measles virus is suspected despite a negative finding, a second sample should be collected no less than 1-2 weeks later.
EquivocalEquivocal samples should be retested. If the result remains equivocal after repeat testing, a second sample should be recollected no less than 1-2 weeks later.
PositivePresence of detectable measles virus IgG antibodies. A positive result generally indicates past exposure to measles virus or previous vaccination.

CPT code(s):  86765
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Qualitative determination of IgG antibodies to measles.


Methodology: 
Chemiluminescence
Synonyms: 

Measles, Measles Antibody, Measles IgG Antibody, Rubeola antibody, RUBEG,


Clinical significance: 

Measles (rubeola) is a highly contagious disease resulting from infection by rubeola virus. Serology tseting for measles can ascertain the immune status of previously vaccinated individuals and detect seroconverstion in recently vaccinated individuals. A positive rubeola IgG antibody in the absence of a current or recent infection is evidence of immunity to rubeola. Acute infection is diagnosed by testing for rubeola IgM antibody.


Doctoral Director(s): 
Benjamin Andress, PhD, DABCC
Hoi-Ying Elsie Yu, PhD, DABCC, FADLM
Review Date:  11/25/2024

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