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Specimen Collection Manual and Test Catalog

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LEGIONELLA ANTIGEN, URINE

Geisinger Epic Procedure Code:  LAB2600    Geisinger Epic ID:  39172

SPECIMEN COLLECTION
Specimen type: 

Random urine


Preferred collection container: 
Specimen required: 

5 mL aliquot urine; minimum 2 mL.



SPECIMEN PROCESSING
Processing instructions: 

Do not centrifuge.


Transport temperature: 

Refrigerated (preferred). Room temperature (stable 24 hours) and frozen specimens also acceptable.


Specimen stability: 

Room temperature: 24 hours. 2-8°C: 14 days. Frozen: 6 months.


Rejection criteria: 

Specimen stability exceeded; specimen grossly hemolyzed.



TEST DETAILS
Reference interval: 

Negative.


CPT code(s):  87449
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Antigen detection to Legionella.


Methodology: 
Rapid Immunochromatographic Assay
Synonyms: 

LEGIONELLA URINARY ANTIGEN, LEGAGB


Clinical significance: 

Legionella pneumophila is responsible for 80-90% of cases of Legionella infection, with serogroup 1 accounting for 70 to 80% of all legionellosis. This test will not detect infections caused by other L. pneumophila serogroups or Legionella species. Although this is a highly sensitive and specific test, a negative antigen result does not fully exclude infection with L. pneumophila serogroup 1. CDC recommends urinary antigen assay and selective respiratory culture to detect causative agents other than L. pneumophila serogroup 1 and to recover L. pneumophila serogroup 1 when antigen is negative.


Doctoral Director(s): 
Benjamin Andress, PhD, DABCC
Hoi-Ying Elsie Yu, PhD, DABCC, FADLM
Review Date:  11/20/2024

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