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Specimen Collection Manual and Test Catalog

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CALCIUM, FRACTIONATED EXCRETION

Geisinger Epic Procedure Code:  LAB1920    Geisinger Epic ID:  21427

SPECIMEN COLLECTION
Specimen type: 

Serum OR plasma* AND random urine


Preferred collection container: 
Specimen required: 

2 mL serum OR plasma AND 5 mL urine. Collection of serum and urine specimens must be within 8 hours.


Special notes: 

*Lithium heparin plasma is acceptable from in-house collection.



SPECIMEN PROCESSING
Processing instructions: 

Allow serum to clot. Centrifuge to separate serum or plasma within 2 hours of collection.


Transport temperature: 

Refrigerated.


Specimen stability: 

See individual member listing.


Rejection criteria: 

Serum (or plasma) and urine specimens collected more than 8 hours apart are not acceptable.



TEST DETAILS
Reference interval: 

0.01-0.02


Interpretation guide: 

< 0.01 suggestive of familial hypocalciuric hypercalcemia 
>0.02 suggestive of hyperparathyroidism


Critical values/courtesy alerts: 
See individual member listing.
CPT code(s):  82310 x 2, 82565, 82570
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Calcium fractional excretion, calcium-serum, calcium-random urine, creatinine-serum, creatinine-random urine.


Methodology: 
Spectrophotometric (Colorimetric)
Synonyms: 

CAFEB, CALCIUM FRACTIONAL EXCRETION


Clinical significance: 

The test can aid in the differentiation between familial hypocalciuric hypercalcemia and hyperparathyroidism.


Doctoral Director(s): 
Hoi-Ying Elsie Yu, PhD, DABCC, FADLM
Sheng-Ying (Margaret) Lo, PhD, DABCC
Review Date:  12/27/2024

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