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Specimen Collection Manual and Test Catalog

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HTLV I/II ANTIBODY,W/REFLEX TO CONFIRMATORY ASSAY

Geisinger Epic Procedure Code:  LAB2498    Geisinger Epic ID:  19000

SPECIMEN COLLECTION
Specimen type: 

Serum (preferred) or plasma


Preferred collection container: 
Alternate collection container: 
6 mL red-top (plain, non-serum separator) tube
3 mL lavender-top (K2 EDTA) tube
Specimen required: 

2 mL serum (preferred) or plasma; minimum 1 mL.



SPECIMEN PROCESSING
Processing instructions: 

Allow serum to clot. Centrifuge serum or plasma 10 minutes at 3000 rpm.


Transport temperature: 

Refrigerated.


Specimen stability: 

Room temperature: Unacceptable. Refrigerated: 7 days. Frozen: 30 days.


Rejection criteria: 

Specimens received at room temperature.



TEST DETAILS
CPT code(s):  86790
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

HTLV-I/-II Antibody, HTLV I/II, WESTERN BLOT [8511X]


Methodology: 
Screen: Immunoassay. Confirmation: Western Blot
Synonyms: 

Human T-cell Lymphotropic Virus, HTLV 1/2 Progressive, HT12, Quest test code 36175


Clinical significance: 

HTLV-I is associated with adult T-cell lymphoblastic leukemia and B-cell chronic lymphocytic leukemia. HTLV-II is less common and is associated with neoplasias of the CD8 T lymphocytes. Blood donor screening began in 1998. Line Immunoassay (LIA) is used for confirmation of antibody testing.


Review Date:  12/17/2024

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