Specimen Collection Manual and Test Catalog

4 mL aliquot of serum; minimum 2 mL.

Gel barrier tubes must be aliquotted.

The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been...determined to interfere with assays for... Cholesterol, Uric Acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.

Allow to clot. Centrifuge 10 minutes at 3000 rpm.

Refrigerated.

Room temperature: 24 hours. Refrigerated (cold packs): Stable 7 days. Frozen: Stable 15 days.

Specimen is grossly lipemic; moderately to grossly icteric.

Interpretive report.

Cardio IQ® Cholesterol, Total; Cardio IQ® HDL Cholesterol; Cardio IQ® Triglycerides; Cardio IQ® Non-HDL and Calculated Components; Cardio IQ® Lipoprotein Fractionation, Ion Mobility; Cardio IQ® Apolipoprotein B; Cardio IQ® Lipoprotein (a) If Triglyceride is >400 mg/dL, Cardio IQ® Direct LDL will be performed at an additional charge (CPT code(s): 83721). Enzymatic • Fixed Rate Time Nephelometry • Immunoturbidometric • Ion Mobility • Spectrophotometry (SP)

Advanced lipid profile, CARDIO IQ ADVANCED LIPID PANEL, VAP, Quest test code 92145