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Specimen Collection Manual and Test Catalog

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RPR

Geisinger Epic Procedure Code:  LAB2976    Geisinger Epic ID:  18030

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
6 mL red-top (plain, non-serum separator) tube
Specimen required: 

0.5 mL serum; minimum 0.5 mL. 
Pediatric specimens: Four (4) microtainers required.



SPECIMEN PROCESSING
Processing instructions: 

Allow serum to clot. Centrifuge and submit 0.5 mL serum.


Transport temperature: 

Refrigerated.


Specimen stability: 

Serum: Stable five (5) days at 2-8°C.


Rejection criteria: 

Stability exceeded or if grossly hemolyzed.



TEST DETAILS
Reference interval: 

Nonreactive.


Additional information: 

Department of Health notified for PA residents if positive.


CPT code(s):  86592
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Qualitative and semiquantitative detection of reagin antibodies, RPR and titer


Methodology: 
Agglutination/Flocculation
Synonyms: 

Rapid plasma reagin, Treponema pallidum


Clinical significance: 

RPR is a qualitative and semiquantitative nontreponemal flocculation test for the detection of reagin antibodies in human serum as a screening test in syphilis serology.


Doctoral Director(s): 
Benjamin Andress, PhD, DABCC
Hoi-Ying Elsie Yu, PhD, DABCC, FADLM
Review Date:  12/04/2024

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