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Specimen Collection Manual and Test Catalog

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CYCLOSPORA AND ISOSPORA EXAM

Geisinger Epic Procedure Code:  LAB2158    Geisinger Epic ID:  31027

SPECIMEN COLLECTION
Specimen type: 

Preserved stool (10% formalin, SAF, or ECOFIX)


Preferred collection container: 
Alternate collection container: 
Para-Pak 10% Buffered Neutral Formalin
Specimen required: 

Stool.


Special notes: 

Transfer stool within 30 minutes of collection into suitable vial. Fill to the line on the transport vial.


Patient preparation: 

Stool must not contain residual barium from diagnostic tests



SPECIMEN PROCESSING
Processing instructions: 

Do not centrifuge. Do not aliquot.


Transport temperature: 

Room temperature.


Specimen stability: 

Room temperature: 30 days. Refrigerated: Unacceptable. Frozen: Unacceptable.


Rejection criteria: 

Specimen received frozen. Unpreserved stool.



TEST DETAILS
CPT code(s):  87015, 87207
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Cyclospora Examination, Isospora Examination, Concentration.


Methodology: 
Stain - Modified Acid-Fast Smear
Synonyms: 

CYISO, Quest test code 10018X


Clinical significance: 

Cyclospora cayetanensis and Isospora belli are coccidian parasites which cause malaise, low grade fever, and diarrhea. Fatigue, anorexia, vomiting, myalgia and weight loss occur. The clinical presentation for those patients infected with either disease is similar.


Review Date:  08/27/2025

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