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Specimen Collection Manual and Test Catalog

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EBV EARLY ANTIGEN IGG ANTIBODY

Geisinger Epic Procedure Code:  LAB2229    Geisinger Epic ID:  32952

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
6 mL red-top (plain, non-serum separator) tube
Specimen required: 

1 mL serum. Minimum 0.5 mL



SPECIMEN PROCESSING
Processing instructions: 

Allow to clot. Centrifuge and aliquot.


Transport temperature: 

Refrigerated.


Specimen stability: 

Room temperature: 4 days. Refrigerated: 7 days. Frozen: 30 days.


Rejection criteria: 

Received past stability.



TEST DETAILS
CPT code(s):  86663
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Methodology: 
Immunoassay
Synonyms: 

EBV Early Antigen-Diffuse, EBV EA-D, EBVEAR, Quest test code 15447


Clinical significance: 

Primary infection by EBV causes infectious mononucleosis, usually a self-limiting disease in children and young adults. Infection with EBV can cause lymphoproliferative disorders including tumors. IgG recognizing Early Antigen D typically appears within a month after clinical presentation and is transient, lasting only 3-4 months. Persistently elevated levels suggest reactivation or persistence of EBV infection.


Doctoral Director(s): 
Hoi-Ying Elsie Yu PhD, DABCC, FADLM
Review Date:  12/19/2024

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