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Specimen Collection Manual and Test Catalog

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TOXOPLASMA GONDII IGG ANTIBODY

Geisinger Epic Procedure Code:  LAB3181    Geisinger Epic ID:  19103

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
6 mL red-top (plain, non-serum separator) tube
Specimen required: 

0.5 mL serum; minimum 0.2 mL



SPECIMEN PROCESSING
Processing instructions: 

Allow to clot. Centrifuge and submit 0.5 mL serum.


Transport temperature: 

Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable.


Specimen stability: 

Room temperature: 8 hours. 2-8°C: 4 days. Frozen: 6 months.


Rejection criteria: 

Specimen stability exceeded; specimen grossly hemolyzed.



TEST DETAILS
Interpretation guide: 
ResultInterpretation
NegativeAbsence of detectable Toxoplasma gondii IgG antibodies. A negative result does not rule out acute infection. The test usually scores negative in infected patients during the incubation period and early stages of infection. If exposure to Toxoplasma gondii is suspected despite a negative finding, a second sample should be collected and tested no less than one or two weeks later.
EquivocalSuggest a second sample be collected and tested one to two weeks later.
PositivePresence of detectable Toxoplasma gondii IgG antibodies. A positive result generally indicates either recent or past exposure to the pathogen. If IgG test scores positive in the presence of IgM antibodies, recent infection may be postulated. If IgG test scores positive in the absence of IgM antibodies, past infection may be postulated.


NOTE: This test is for the qualitative determination of IgG antibodies to Toxoplasma gondii.


CPT code(s):  86777
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Antibody detection to Toxoplasma IgG.


Methodology: 
Chemiluminescence
Synonyms: 

Toxoplasma gondii IgG Ab, Toxoplasma IgG antibody, Toxoplasma Antibody IgG


Clinical significance: 

This test is useful for determining if a patient has had recent or past exposure to Toxoplasma gondii. IgG antibodies to toxoplasma gondii is indicative of previous exposure (recent or past). A single positive result should not be used to diagnose recent infection.


Doctoral Director(s): 
Benjamin Andress, PhD, DABCC
Hoi-Ying Elsie Yu, PhD, DABCC, FADLM
Review Date:  11/26/2024

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