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Specimen Collection Manual and Test Catalog

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MYELIN-ASSOCIATED-GLYCOPROTEIN (MAG)-SGPG AB (IGM),EIA

Geisinger Epic Procedure Code:  LAB2725    Geisinger Epic ID:  35859

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
3.5 mL gold-top (serum separator) tube
Specimen required: 

1 mL (minimum 0.2 mL) serum


Patient preparation: 

Overnight fasting preferred.



SPECIMEN PROCESSING
Transport temperature: 

Refrigerated.


Specimen stability: 

Room temperature: 2 days. Refrigerated: 2 weeks. Frozen: 1 month.


Rejection criteria: 

Stability limits exceeded.



TEST DETAILS
Reference interval: 

Accompanies report.


CPT code(s):  83520
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Methodology: 
Enzyme Immunoassay (EIA)
Synonyms: 

Quest test code 37078, SGPGAB


Clinical significance: 

Myelin associated glycoprotein (MAG) and sulphated glucuronyl paragloboside (SGPG) antibodies are present in a subgroup of sensory demyelinating neuropathies. Axonal neuropathies can present with only monoclonal IgM anti-SGPG activity. Presence of anti-SGPG antibodies alone is more characteristic of axonal non-demyelinating neuropathy. There is a relationship between the titer of anti-MAG antibodies and the degree of demyelination.


Review Date:  12/03/2024

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