Specimen Collection Manual and Test Catalog
RECOMBX(R) ZIC4 AUTOANTIBODY TEST
Geisinger Epic Procedure Code: LAB3292 Geisinger Epic ID: 35847SPECIMEN COLLECTION
Specimen type:
Serum (preferred) or CSF (acceptable but not the preferred specimen)
Preferred collection container:
Alternate collection container:
6 mL red-top (plain, non-serum separator) tube
Specimen required:
2 mL serum (preferred) or CSF (also acceptable); minimum 0.5 mL.
Special notes:
CSF (2 mL; minimum 0.5 mL) in sterile-leak-proof container is acceptable but is not the preferred specimen.
SPECIMEN PROCESSING
Processing instructions:
Serum must be separated from cells within 48 hours of collection.
Transport temperature:
Refrigerated.
Specimen stability:
Room temperature: 72 hours. Refrigerated: 28 days. Frozen: 28 days.
Rejection criteria:
Stability limits exceeded.
TEST DETAILS
Reference interval:
CPT code(s):
83520 Accompanies report.
Note: The billing party has sole responsibility for CPT coding. Any
questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Methodology:
Automated Nanoliter Scale Immunoassay
Synonyms:
Anti-Zic4, Anti-Zic4 Ab, Quest test code 4689, Athena test code 127, ZIC4
Clinical significance:
Review Date:
12/03/2024 Anti-Zic4 antibody is usually found in patients with paraneoplastic cerebellar degeneration and is associated with small cell lung carcinoma. This semi-quantitative assay may be useful in monitoring therapeutic responses in select cases.
Performing Locations