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Specimen Collection Manual and Test Catalog

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17 OH PROGESTERONE

Geisinger Epic Procedure Code:  LAB1484    Geisinger Epic ID:  36103

SPECIMEN COLLECTION
Specimen type: 

Serum (preferred) or plasma.


Preferred collection container: 
Alternate collection container: 
6 mL dark blue-top (K2 EDTA) tube
3 mL green/black top lithium heparin tube
3 mL lavender-top (K2 EDTA) tube
4 mL green/green-top (sodium heparin) tube
Specimen required: 

0.5 mL serum or plasma; minimum 0.25 mL.


Special notes: 

Serum separator tubes are not acceptable for testing. Please submit a separate aliquot for testing.



SPECIMEN PROCESSING
Processing instructions: 

Separate serum after clotting and submit aliquot.


Transport temperature: 

Refrigerated.


Specimen stability: 

Room temperature: 48 hours. Refrigerated: 7 days. Frozen: 2 years.


Rejection criteria: 

Stability limits exceeded. Specimens collected in serum separator tube.



TEST DETAILS
Reference interval: 

Accompanies report.


CPT code(s):  83498
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

17-OH progesterone.


Methodology: 
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Synonyms: 

17 Hydroxyprogesterone, QUEST test code 17180


Clinical significance: 

17-Hydroxyprogesterone is elevated in patients with congenital adrenal hyperplasia (CAH). CAH is a group of autosomal recessive diseases, characterized by a deficiency of cortisol and an excess of ACTH concentration. 17-Hydroxyprogesterone is also useful in monitoring cortisol replacement therapy and in evaluating infertility and adrenal and ovarian neoplasms.


Doctoral Director(s): 
Randin Nelson MD
Review Date:  12/04/2024

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