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Specimen Collection Manual and Test Catalog

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FISH UROVYSION

Geisinger Epic Procedure Code:  LAB4105    Geisinger Epic ID:  37264

SPECIMEN COLLECTION
Specimen type: 

Voided urine


Preferred collection container: 
Alternate collection container: 
Quest urine preservative transport kit
Specimen required: 

50 mL voided urine collected in PreservCyt®


Special notes: 

50 mL voided urine collected in PreservCyt® or Perform bladder washing collection (50 mL) at the physician's office in a sterile 100 mL urine specimen container. Mix bladder washing with CytoLyt® or ethanol 50% in a 1:1 solution.



SPECIMEN PROCESSING
Processing instructions: 

A urine preservative transport kit, with handling instructions, is available upon request. Perform urine collection (50 mL) at the physician's office or Patient Service Center (PSC) in a sterile 100 mL urine specimen container. Mix voided urine with CytoLyt® or ethanol 50% in a 1:1 solution.


Transport temperature: 

Refrigerated


Specimen stability: 

Less than 72 hours from collection to processing



TEST DETAILS
CPT code(s):  88121
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Methodology: 
Fluorescence In Situ Hybridization (FISH)
Synonyms: 

UroVysion, UroVysion FISH, UroVysion assay, FISH for bladder cancer. Quest test code 10107


Clinical significance: 

The UroVysion TM assay is a FISH assay for the detection of urothelial carcinoma. The UroVysion TM probe set contains probes to the centromeres of chromosomes 3, 7, and 17 snd a locus-specific probe for 9p21 band.


Doctoral Director(s): 
Randin Nelson MD
Review Date:  01/02/2024

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