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Specimen Collection Manual and Test Catalog

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TOXICOLOGY, URINE SCREEN W/ CONFIRMATION

Geisinger Epic Procedure Code:  LAB3177    Geisinger Epic ID:  37650

SPECIMEN COLLECTION
Specimen type: 

Random urine


Preferred collection container: 
Specimen required: 

15 mL aliquot AND 5 mL aliquot urine, as above; minimum 10 mL and 1 mL, respectively.



SPECIMEN PROCESSING
Transport temperature: 

Refrigerated (preferred) or room temperature.


Specimen stability: 

Room temperature: 2 days. Refrigerated: 14 days


Rejection criteria: 

Stability limits exceeded.



TEST DETAILS
Reference interval: 

Negative. 
 

Screen cutoff concentration:

Amphetamines500 ng/mL
Benzodiazepines100 ng/mL
Cannabinoids50 ng/mL
Cocaine metabolite150 ng/mL
Fentanyl5 ng/mL
Hydrocodone/Hydromorphone300 ng/mL
Methadone metabolite100 ng/mL
Morphine/Codeine300 ng/mL
Oxycodone/Oxymorphone100 ng/mL

Additional information: 

Screening results are presumptive and can only be used for medical purposes. Guide to drugs of abuse panels.


CPT code(s):  80307
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Amphetamines screen 
Benzodiazepines screen 
Cannabinoids screen 
Cocaine metabolite screen 
Fentanyl screen 
Hydrocodone/Hydromorphone screen 
Methadone metabolite screen
Morphine/Codeine screen 
Oxycodone/Oxymorphone screen 
Positive screening results are automatically confirmed by LC-MS/MS at an additional charge.


Methodology: 
EMIT
Homogeneous enzyme immunoassay
KIMS
Synonyms: 

Drug screen, urine drug screen, urine toxicology screen, tox screen with confirmation, TOXUC


Doctoral Director(s): 
Hoi-Ying Elsie Yu, PhD, DABCC, FADLM
Sheng-Ying (Margaret) Lo, PhD, DABCC
Review Date:  12/09/2025

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