Skip to main content

Specimen Collection Manual and Test Catalog

  or
  or
  or

URINE PROTEIN ELECTROPHORESIS REFLEX PROFILE, 24 HOUR URINE

Geisinger Epic Procedure Code:  LAB3225    Geisinger Epic ID:  37747

SPECIMEN COLLECTION
Specimen type: 

24-hour urine collection


Preferred collection container: 
Specimen required: 

15 mL aliquot AND 5 mL aliquot of 24-hour urine, as above; minimum 10 mL and 2 mL, respectively.


Special notes: 

Mix well, estimate total volume from 24-hour urine container. Remove required aliquot, record total volume on both aliquot tube and request slip (if applicable).



SPECIMEN PROCESSING
Processing instructions: 

Do not centrifuge.


Transport temperature: 

Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable.


Specimen stability: 

Room temperature: 8 hours; Refrigerated (2-8 C): 72 hours; Frozen: 6 months.


Rejection criteria: 

Stability limits exceeded; less than 6 mL of urine received.



TEST DETAILS
Reference interval: 

No abnormal peaks detected.


CPT code(s):  84166
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Urine protein electrophoresis with interpretation. Based on pathologist review, testing may reflex to Urine Immunofixation (UIFE).


Methodology: 
Electrophoresis
Synonyms: 

Protein electrophoresis, 24-hour urine, EPGU 24-hour urine, EPGU24


Clinical significance: 

Urine protein electrophoresis evaluates the presence of albumin and globulin fractions in urine to aid in the diagnosis of plasma cell dyscrasias such as Multiple Myeloma, Waldenstrom Macroglobulinemia, or AL Amyloidosis.


Doctoral Director(s): 
Benjamin Andress, PhD, DABCC
Hoi-Ying Elsie Yu, PhD, DABCC, FADLM
Review Date:  01/14/2025

Performing Locations