Specimen Collection Manual and Test Catalog

One full 3.5 mL gold-top serum separator tube (preferred).

Allow to clot. Centrifuge and submit one full 3.5 mL gold-top serum separator tube.

Refrigerated

5 days 2-8°C.

Specimen will be rejected if stability limit has been exceeded or if specimen is hemolyzed, lipemic or icteric.

Nonreactive.

Qualitative detection of antibodies to Treponema pallidum (screening) by chemiluminescence, with reflex to RPR and Treponemal pallidum particle agglutination when appropriate. If the qualitative T. pallidum antibody result is negative, the testing is complete. If the qualitative detection of antibodies is positive, then a quantitative RPR will be performed. If the RPR is positive, the patient has active syphilis. If the RPR is negative, a Treponemal pallidum particle agglutination assay will be performed. If the T. pallidum particle agglutination is positive, the patient had a probable past syphilis infection. If the Treponemal pallidum is negative, the patient likely does not have syphilis.

SYPPRO

Useful for aiding in the diagnosis of recent or past Treponema pallidum infection and for routine prenantal screening. This test is not useful for diagnosis of congenital syphilis or for monitoring response to treatment.