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Specimen Collection Manual and Test Catalog

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IMMATURE PLATELET FRACTION

Geisinger Epic Procedure Code:  LAB2524    Geisinger Epic ID:  41189

SPECIMEN COLLECTION
Specimen type: 

Whole blood


Preferred collection container: 
Alternate collection container: 
Lavender-top (K2 EDTA) microcollection tube
Specimen required: 

3 mL lavender-top (K2 EDTA) tube collected MUST be properly filled to at least 1.5 mL (half the fill volume of the tube). 
Lavender-top (K2EDTA) microcollection tube MUST be properly filled to at least 250 uL (half the fill volume of the tube). 
Sample MUST be collected at performing laboratory site. This test is not performed at certain clinic locations or Geisinger Jersey Shore Hospital.



SPECIMEN PROCESSING
Processing instructions: 

DO NOT CENTRIFUGE.


Transport temperature: 

Drawn at performing sites only. DO NOT TRANSPORT or send through the pneumatic tube system. 


Specimen stability: 

Room temperature: 24 hours.


Rejection criteria: 

Clotted, frozen, hemolyzed, overfilled, underfilled, exceeded stability limits or sent through a pneumatic tube system.



TEST DETAILS
Reference interval: 

0.7-6.7%
Established from a study performed at GMC and GWV in 2012.


Additional information: 

Potential related available add on testing includes: CBC with WBC differential (LAB1963), CBC (LAB1961), HGB (LAB2461), HCT (LAB2400), PLT (LAB2863). 
See individual test requirements.


CPT code(s):  85055
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Immature platelet fraction and platelet count.


Methodology: 
Electronic resistance detection enhancd by hydrodynamic focusing and flow cytometry
Synonyms: 

Reticulated platelets; immature platelets, IPFB


Clinical significance: 

The IPF can be utilized in the evaluation of thrombocytopenia. The IPF is generally elevated in platelet consumption/destruction disorders or in bone marrow recovery. Thrombocytopenia with a low IPF indicates decreased bone marrow production. https://pubmed.ncbi.nlm.nih.gov/16393688/


Doctoral Director(s): 
Mary Dhesi MD
Review Date:  01/08/2025

Performing Locations