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Specimen Collection Manual and Test Catalog

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ALKALINE PHOSPHATASE ISOENZYMES

Geisinger Epic Procedure Code:  LAB1548    Geisinger Epic ID:  17782

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
3.5 mL gold-top (serum separator) tube
Specimen required: 

2 mL aliquot of serum; minimum 1 mL.


Special notes: 

Centrifuge within 30 minutes of collection.


Patient preparation: 

Overnight fasting is preferred.



SPECIMEN PROCESSING
Processing instructions: 

Allow to clot. Centrifuge and aliquot.


Transport temperature: 

Room temperature (preferred). Refrigerated or frozen specimen also acceptable.


Specimen stability: 

Room Temperature: 7 days. Refrigerated: 21 days. Frozen: 21 days.


Rejection criteria: 

Stability limits exceeded.



TEST DETAILS
CPT code(s):  84075, 84080
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Alkaline Phosphatase, Intestinal Isoenzymes, Bone Isoenzymes, Liver Isoenzymes, Placental Isoenzymes, Macrohepatic Isoenzymes


Methodology: 
Electrophoresis
Spectrophotometric (Colorimetric)
Synonyms: 

Alkaline phosphatase isoenzymes, ALKPI, Quest test code 231


Clinical significance: 

When the Total Alkaline Phosphatase activity is increased, the Isoenzymes are useful in determining the source of the increased activity.


Review Date:  12/19/2024

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