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Specimen Collection Manual and Test Catalog

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T-CELL RECEPTOR GAMMA GENE REARRANGE,PCR

Geisinger Epic Procedure Code:  LAB3120    Geisinger Epic ID:  43719

SPECIMEN COLLECTION
Specimen type: 

Whole blood (preferred) or bone marrow aspirate


Preferred collection container: 
Alternate collection container: 
3 mL lavender-top (K2 EDTA) tube
Specimen required: 

5 mL EDTA whole blood, minimum 3mL; or 3 mL bone marrow aspirate, minimum 1 mL



SPECIMEN PROCESSING
Transport temperature: 

Room temperature


Specimen stability: 

Room temperature: 7 days. Refrigerated: 7 days.



TEST DETAILS
CPT code(s):  81342, 84999
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Methodology: 
Fragment Analysis
Polymerase Chain Reaction (PCR)
Synonyms: 

Quest test code 90509, T-cell receptor clonality, TCR-gamma clonality, TCRGGR


Clinical significance: 

This assay which interrogates the T-cell receptor gamma locus (TCRG) by a PCR method based on the BIOMED-2 consensus, is useful for establishing clonality of T-cell lymphoid neoplasms and identification of minimal residual disease or early recurrence in patients with a previous diagnosis of a T-cell neoplasm. It can be used in association with the T-cell receptor beta (TCRB) PCR assay (Test code 91446 or TCRG/TCRB combo test code 91445), since false-negative results can occur in up to 5-10% of T-cell malignancies when testing for TCRG PCR only


Review Date:  12/05/2024

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