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Specimen Collection Manual and Test Catalog

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LEUKOCYTE ADHESION DEFICIENCY(LAD)EVAL(CD15S,CD18)

Geisinger Epic Procedure Code:  LAB2604    Geisinger Epic ID:  44109

SPECIMEN COLLECTION
Specimen type: 

Whole blood


Preferred collection container: 
Specimen required: 

4 mL whole blood


Special notes: 

Due to the extremely short stability this specimen must be received in Referred Tests by 2pm on the day of collection. Patients should only be collected at GMC, GWV, and GCMC.



SPECIMEN PROCESSING
Processing instructions: 

Specimen should be shipped the same day as collection.


Transport temperature: 

Room temperature.


Specimen stability: 

Room temperature: 72 hours.


Rejection criteria: 

Hemolysis • Lipemia • Icterus • Clotted specimens • Received refrigerated or frozen



TEST DETAILS
CPT code(s):  88184, 88185
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Methodology: 
Flow Cytometry
Synonyms: 

Quest test code 19815, LAD


Clinical significance: 

LAD is an autosomal recessive immunodeficiency disorder associated with recurrent bacterial and fungal infections. Two forms of LAD have been described. LAD-1 is associated with defective expression of CD18 by neutrophils, whereas LAD-2 is associated with defective expression of CD15s (sialyl-Lewis X).


Review Date:  12/04/2024

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