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Specimen Collection Manual and Test Catalog

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HISTAMINE, PLASMA

Geisinger Epic Procedure Code:  LAB2462    Geisinger Epic ID:  45090

SPECIMEN COLLECTION
Specimen type: 

Plasma


Preferred collection container: 
Specimen required: 

1 mL plasma, minimum 0.5 mL, collected in EDTA tube


Special notes: 

See Specimen Processing Instructions


Patient preparation: 

Avoid taking allergy causing drugs, antihistamines, oral corticosteroids, and substances which block H2 receptors for at least 24 hours before collection.



SPECIMEN PROCESSING
Processing instructions: 

Centrifuge immediately and freeze plasma in a plastic vial.


Transport temperature: 

Frozen.


Specimen stability: 

Room temperature: 24 hours. Refrigerated: 24 hours. Frozen: 7 days.


Rejection criteria: 

Hemolysis. Lipemia. Specimens received refrigerated or at room temperature.



TEST DETAILS
Reference interval: 

Histamine, Plasma < or = 1.8 ng/mL


CPT code(s):  83088
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Methodology: 
Enzyme Immunoassay (EIA)
Synonyms: 

Quest test code 36586, HIST


Clinical significance: 

Clinical Significance: Histamine is a mediator of the allergic response. Histamine release causes itching, flushing, hives, vomiting, syncope, and even shock. In addition, some patients with gastric carcinoids may exhibit high concentrations of histamine.


Review Date:  12/04/2024

Performing Locations