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Specimen Collection Manual and Test Catalog

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ACETYLCHOLINE RECEPTOR BLOCKING AB

Geisinger Epic Procedure Code:  LAB1509    Geisinger Epic ID:  45091

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
6 mL red-top (plain, non-serum separator) tube
Specimen required: 

0.2 mL serum


Special notes: 

See Specimen Processing Instructions.



SPECIMEN PROCESSING
Processing instructions: 

Centrifuge within 1 hour of collection.


Transport temperature: 

Refrigerated (cold packs).


Specimen stability: 

Room temperature: 14 days. Refrigerated: 14 days. Frozen: 30 days.



TEST DETAILS
CPT code(s):  86042
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Methodology: 
Immunoassay
Synonyms: 

ACETYLCHOLINE RECEPTOR BLOCKING ANTIBODY, Quest test code 34459, ARBAB


Clinical significance: 

Myasthenia gravis (MG) is a neuromuscular disorder characterized by muscle weakness, most commonly due to autoantibody-mediated loss of functional acetylcholine receptors (AChR) in the neuromuscular junction. This assay is most useful when the acetylcholinesterase receptor modulating antibodies are positive. The assay for blocking antibodies is useful in monitoring response to therapy.


Review Date:  12/04/2024

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