Skip to main content

Specimen Collection Manual and Test Catalog

  or
  or
  or

ANTI-STREPTOLYSIN O

Geisinger Epic Procedure Code:  LAB3096    Geisinger Epic ID:  45845

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
6 mL red-top (plain, non-serum separator) tube
Specimen required: 

1 mL serum; minimum 0.5 mL



SPECIMEN PROCESSING
Transport temperature: 

Frozen.


Specimen stability: 

Room temperature: 3 days. Refrigerated: 5 days. Frozen: 30 days (-20°C).



TEST DETAILS
Interpretation guide: 

False-positive ASO titers can be due to increased levels of serum beta-lipoprotein produced in liver disease and by "contamination" of serum by Bacillus cereus and Pseudomonas species. ASO is not sensitive for the diagnosis of streptococcal pyoderma


Additional information: 

Monday-Friday: Morning, Evening, Night. Saturday Morning; Sunday Night; Report available: Next Day.


CPT code(s):  86060
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Methodology: 
Immunoturbidity
Synonyms: 

Quest test code 265, ASO, antistreptolysin, ASOAB


Clinical significance: 

This test is a sensitive test for recent streptococcal infection. A rise in ASO begins about one week after infection and peaks two to four weeks later. ASO levels do not rise with cutaneous infections. In the absence of complications or reinfection, the ASO level will fall to preinfection levels within 6 to 12 months. Over 80% of patients with acute rheumatic fever and 95% of patients with acute glomerulonephritis due to streptococci have elevated levels of ASO.


Review Date:  12/05/2024

Performing Locations