Skip to main content

Specimen Collection Manual and Test Catalog

  or
  or
  or

METANEPHRINES, FRACTIONATED, LCMSMS, 24-HOUR URINE

Geisinger Epic Procedure Code:  LAB2665    Geisinger Epic ID:  45918

SPECIMEN COLLECTION
Specimen type: 

Preserved urine from 24-hour collection


Preferred collection container: 
Specimen required: 

5 mL preserved urine from a 24-hour collection. minimum 1.5 mL.


Patient preparation: 

It is preferable for the patient to be off medications for three days prior to collection. Patient should avoid tobacco, tea, coffee, for three days prior to specimen collection. Common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference. Medications which are alpha agonists (Aldomet), alpha blockers (Dibenzyline) should be avoided 18-24 hours prior to specimen collection.



SPECIMEN PROCESSING
Processing instructions: 

Lab personnel (to be determined per site) will test the pH of the urines and adjust to less than 3.0 using 6N HCl before Referred Testing ships the specimen. Record 24-hour urine volume and patient's age on test request form and urine vial.


Transport temperature: 

Acidified (preserved) urine: Room temperature or refrigerated.


Specimen stability: 

Room temperature: 10 days. Refrigerated: 14 days. Frozen: 30 days.


Rejection criteria: 

Urine collected with boric acid.



TEST DETAILS
CPT code(s):  83835
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Metanephrine, Normetanephrine, Total Metanephrines


Methodology: 
Chromatography/Mass Spectrometry
Synonyms: 

Quest test code 14962, META24


Clinical significance: 

Useful in the evaluation of pheochromocytoma.


Review Date:  12/20/2024

Performing Locations