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Specimen Collection Manual and Test Catalog

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HEMOGLOBIN S POST TRANSFUSION ASSESSMENT

Geisinger Epic Procedure Code:  LAB2420    Geisinger Epic ID:  56534

SPECIMEN COLLECTION
Specimen type: 

Whole blood


Preferred collection container: 
Specimen required: 

5 mL EDTA whole blood, minimum 1 mL



SPECIMEN PROCESSING
Transport temperature: 

Refrigerated.


Specimen stability: 

Room temperature: 72 hours. Refrigerated: 7 days. Frozen: Unacceptable.


Rejection criteria: 

Stability limit exceeded. Hemolysis. Clotted specimen.



TEST DETAILS
CPT code(s):  83020, 85660
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Hemoglobinopathy Screen, and confirmation by HPLC


Methodology: 
Electronic Sizing and Counting/Cytometry – Capillary Electrophoresis followed by, if necessary, High Performance Liquid Chromatography, Solubility
Synonyms: 

HGBSPT, Quest code 135251


Clinical significance: 

This profile is to be used for monitoring the effects of transfusion/exchange transfusion and hemoglobin F levels post hydroxyurea treatment in patients with known sickle cell anemia or sickle cell disease. The report will include the percentage of Hemoglobin S (HbS), and Hemoglobin C (HbC), if the patient is SC. Please provide the patient's phenotype when requesting this test code. Testing will include Hemoglobinopathy Screen and confirmation by HPLC. No pathologist or technical interpretation will accompany the report.


Doctoral Director(s): 
Randin Nelson MD
Review Date:  11/11/2025

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