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Specimen Collection Manual and Test Catalog

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COPEPTIN

Geisinger Epic Procedure Code:  LAB2075    Geisinger Epic ID:  49242

SPECIMEN COLLECTION
Specimen type: 

Serum or plasma


Preferred collection container: 
Alternate collection container: 
6 mL red-top (plain, non-serum separator) tube
3 mL lavender-top (K2 EDTA) tube
Specimen required: 

1 mL serum; minimum 0.5 mL.



SPECIMEN PROCESSING
Transport temperature: 

Frozen.


Specimen stability: 

Room temperature: 24 hours. Refrigerated: 3 days. Frozen: 28 days.


Rejection criteria: 

Specimen received at room temperature. Gross hemolysis.



TEST DETAILS
CPT code(s):  86255
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Methodology: 
Immunofluorescence Assay
Synonyms: 

Quest test code 37740, C-Terminal pro-vasopressin, CT-proAVP, ADH, Antidiuretic hormone, COPEP


Clinical significance: 

The Copeptin test is used in the diagnosis of central diabetes insipidus and in the differential diagnosis of central or nephrogenic diabetes insipidus. It is also known as “proAVP”. Since Copeptin is more stable than AVP, it is thought to be a better marker than arginine vasopressin (AVP).


Review Date:  12/12/2024

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