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Specimen Collection Manual and Test Catalog

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FIRST TRIMESTER SCREEN

Geisinger Epic Procedure Code:  LAB3710    Geisinger Epic ID:  51953
Test Restriction:  ORDER LIMITED TO GENETICS, MFM, OB

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Specimen required: 

1.5 mL serum, minimum 1 mL


Special notes: 

Collect between 10.0 weeks to 13.9 (13 6/7) weeks. Perform between 10.0 to 13.9 (13 6/7) weeks gestational age. A special Maternal Serum Screen requisition designed to obtain patient data and the patient's informed consent must be used when ordering this test, because these results are influenced by certain patient characteristics. All data requested on the requisition form must be complete to permit accurate interpretation of results.



SPECIMEN PROCESSING
Processing instructions: 

Centrifuge and aliquot.


Transport temperature: 

Room temperature.


Specimen stability: 

Room temperature: 14 days. Refrigerated: 14 days. Frozen: 28 days.


Rejection criteria: 

Gross hemolysis, collected outside of the time period listed above.



TEST DETAILS
CPT code(s):  81508
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

PAPP-A (Pregnancy-associated Plasma Protein-A), hCG, Maternal Risk calculation which includes NT (Nuchal Translucency).


Methodology: 
Calculation
Chemiluminescence
Immunoassay
Synonyms: 

Human Chorionic Gonadotropin (hCG), Nuchal Translucency (NT), Down Syndrome, Trisomy 18 Screen, MSS, 1st Trimester, 1, 1st Trimester Panel, FTS, FTSCRN, Quest test code 16145


Clinical significance: 

To screen for Down Syndrome and Trisomy 18 at 10.0-13.9 weeks gestation. This is not a diagnostic test.


Review Date:  12/05/2024

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