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Specimen Collection Manual and Test Catalog

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ADENOSINE DEAMINASE, PLEURAL FLUID

Geisinger Epic Procedure Code:  LAB1011    Geisinger Epic ID:  51969

SPECIMEN COLLECTION
Specimen type: 

Pleural fluid


Preferred collection container: 
Specimen required: 

0.5 mL pleural fluid; minimum 0.1 mL.



SPECIMEN PROCESSING
Transport temperature: 

Frozen.


Specimen stability: 

Room temperature: 24 hours. Refrigerated: 72 hours. Frozen: 6 months.


Rejection criteria: 

Specimen received at room temperature.



TEST DETAILS
Additional information: 

This test was performed using a kit that has ot been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.


CPT code(s):  84311
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

ADA, pleural fluid.


Methodology: 
Kinetic Spectrophotometric
Synonyms: 

Quest test code 17696, A Deam PF


Clinical significance: 

An elevated level of adenosine deaminase (AD) in human serum, plasma or select body fluids is used as a surrogate marker for inflammation or infectious disease. In CSF, pleural effusions, and pericardial fluid in particular, elevated AD activity has been shown to be associated with tubercular lesions. Additional disease states that may result in elevated AD activity include liver cirrhosis, liver fibrosis, certain malignancies (e.g., lymphoma), viral hepatitis, and autoimmune diseases (e.g., SLE, rheumatoid arthritis).


Review Date:  12/12/2024

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