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Specimen Collection Manual and Test Catalog

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COLLAGEN TYPE I C-TELOPEPTIDE (CTx)

Geisinger Epic Procedure Code:  LAB1012    Geisinger Epic ID:  51973

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
6 mL red-top (plain, non-serum separator) tube
Specimen required: 

1 mL serum (minimum 0.5 mL)


Special notes: 

See specimen processing instructions.


Patient preparation: 

A minimum of 12 hours fasting is required. Fasting morning collection 8-10 am (diurnal variations cause elevated levels at night). Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.



SPECIMEN PROCESSING
Processing instructions: 

Allow blood to clot (10-15 minutes) at room temperature. Centrifuge and separate the serum from the cells. Aliquot and freeze as soon as possible.


Transport temperature: 

Frozen.


Specimen stability: 

Room temperature: 16 hours. Refrigerated: 72 hours. Frozen: 90 days.


Rejection criteria: 

Moderate to gross hemolysis. Grossly lipemic. Grossly icteric.



TEST DETAILS
CPT code(s):  82523
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Methodology: 
Immunoassay
Synonyms: 

Quest test code 17406, Collagen Typ


Clinical significance: 

CTx is useful to assess bone resorption in patients with metabolic bone disease. The test is also useful in monitoring therapy to slow or halt osteoporotic bone loss.


Review Date:  12/19/2024

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