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Specimen Collection Manual and Test Catalog

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INTERLEUKIN-2 RECEPTOR ALPHA CHAIN (IL-2RA/CD25), SOLUBLE

Geisinger Epic Procedure Code:  LAB1041    Geisinger Epic ID:  52089

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Specimen required: 

1 ml frozen serum; minimum 0.5 mL


Special notes: 

IL-2R levels may demonstrate diurnal variation. Recommend IL-2R levels be determined at the same time of day for improved longitudinal comparison. Do not use gel tubes.



SPECIMEN PROCESSING
Processing instructions: 

Centrifuge and aliquot.


Transport temperature: 

Frozen.


Specimen stability: 

Room temperature: Unacceptable. Refrigerated: 24 hours. Frozen: 30 days.


Rejection criteria: 

Serum separator tube (SST). Plasma.



TEST DETAILS
Additional information: 

This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.


CPT code(s):  83520
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

IL-R2 level.


Methodology: 
Immunoassay
Synonyms: 

Quest test code 34298, IL-2 Recep, IL 2R,Soluble IL2-Receptor,CD25,sCD25,Cytokine, IL2 Receptor


Clinical significance: 

Interleukin-2 Receptor Alpha Chain (IL-2Ra/CD25), Soluble - Following stimulation by antigen, IL-2R is expressed on all T cells. IL-2R is released by activated cells into the surrounding extracellular fluid. IL2-R is involved in infectious, inflammatory and autoimmune diseases, cancer, and transplantation. IL-2R Antibodies are used therapeutically. Cytokine levels may demonstrate diurnal variation. Recommend cytokine levels be determined at the same time of day for improved longitudinal comparison.


Review Date:  12/05/2024

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