Skip to main content

Specimen Collection Manual and Test Catalog

  or
  or
  or

HLA-B27 DNA TYPING

Geisinger Epic Procedure Code:  LAB1052    Geisinger Epic ID:  52133

SPECIMEN COLLECTION
Specimen type: 

Whole blood


Preferred collection container: 
Alternate collection container: 
4 mL green/green-top (sodium heparin) tube
Specimen required: 

5mL whole blood; minimum 3 mL


Special notes: 

A separate EDTA (lavender-top), ACD (yellow-top) or Sodium heparin (green-top) tube must be submitted for all HLA testing. If submitted with any other test requiring an EDTA or sodium heparin tube, please submit a separate tube for this test. Do not open tube.



SPECIMEN PROCESSING
Transport temperature: 

Room temperature.


Specimen stability: 

Room temperature: 7 days. Refrigerated: 7 days. Frozen: Unacceptable.


Rejection criteria: 

Received past stability.



TEST DETAILS
CPT code(s):  81374
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Methodology: 
Polymerase Chain Reaction (PCR)
Sequence-specific oligonucleotide probes
Synonyms: 

Quest test code 15584, HLA-B27 DNA ,


Clinical significance: 

This test is used in the evaluation of genetic risk for Ankylosing Spondylitis, uveitis, and several other autoimmune disorders.


Review Date:  12/05/2024

Performing Locations