Skip to main content

Specimen Collection Manual and Test Catalog

  or
  or
  or

DESMOGLEIN ANTIBODIES (1 AND 3)

Geisinger Epic Procedure Code:  LAB1095    Geisinger Epic ID:  52305

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
6 mL red-top (plain, non-serum separator) tube
Specimen required: 

0.3 mL serum; minimum 0.1 mL


Special notes: 

No anticoagulants or preservatives should be added. Avoid using sera exhibiting a high level of lipemia, hemolysis, icterus, or microbial growth. These conditions may cause aberrant test results. Do not use heat-inactivated serum as this affects test results. Blood should be collected fasting for at least one hour after meals to avoid lipemic serum.


Patient preparation: 

Fasting sample preferred.



SPECIMEN PROCESSING
Processing instructions: 

Centrifuge and aliquot.


Transport temperature: 

Refrigerated (cold packs).


Specimen stability: 

Room temperature: 14 days. Refrigerated: 14 days. Frozen: 28 days.



TEST DETAILS
Reference interval: 

High levels of hemolysis • High levels of lipemia • Icterus or microbial growth


CPT code(s):  83520 x2
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Methodology: 
Enzyme-Linked Immunosorbent Assay (ELISA)
Synonyms: 

Quest test code 16033, Desmoglein A, DSG 3,DSG 1,Pemphigus Foliaceus, Pemphigus Vulgaris


Clinical significance: 

To detect the presence of auto antibody specific to Desmoglein 1 and/or 3 in a patients serum as an aid to diagnose type of pemphigus


Review Date:  12/17/2024

Performing Locations