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Specimen Collection Manual and Test Catalog

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THYROGLOBULIN, LC/MS/MS

Geisinger Epic Procedure Code:  LAB1116    Geisinger Epic ID:  52389

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
6 mL red-top (plain, non-serum separator) tube
Specimen required: 

1 mL serum; minimum 0.5 mL



SPECIMEN PROCESSING
Processing instructions: 

Centrifuge and aliquot.


Transport temperature: 

Room temperature.


Specimen stability: 

Room temperature: 6 days. Refrigerated: 7 days. Frozen: 28 days.


Rejection criteria: 

Hemolysis • Lipemia • Plasma • Icteric specimen



TEST DETAILS
Additional information: 

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.


CPT code(s):  84432
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Methodology: 
Chromatography/Mass Spectrometry
Synonyms: 

Quest test code 90810, Thyro LMM


Clinical significance: 

Measurement of thyroglobulin (Tg) is useful in the detection of residual or recurrent thyroid cancer. Many individuals develop auto-antibodies to Tg (Tg Ab) and the presence of Tg Ab interferes with the measurement of immunoassay Tg. The LC/MS/MS assay will provide quantitative measurement of Tg in the presence of Tg Ab.


Review Date:  12/09/2024

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