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Specimen Collection Manual and Test Catalog

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APOLIPOPROTEIN E (APOE) ISOFORM, CSF

Geisinger Epic Procedure Code:  LAB1118    Geisinger Epic ID:  52397

SPECIMEN COLLECTION
Specimen type: 

CSF


Preferred collection container: 
Specimen required: 

0.4 mL CSF; minimum 0.2 mL


Special notes: 

Quest does not perform this test for individuals under the age of 18. Pre-test and post-test counseling is strongly recommended.



SPECIMEN PROCESSING
Transport temperature: 

Frozen.


Specimen stability: 

Room temperature: 72 hours. Refrigerated: 5 days. Frozen: 31 days.


Rejection criteria: 

Specimen collected in a glass, polystyrene, or polycarbonate tube.



TEST DETAILS
Additional information: 

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.


CPT code(s):  82542
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Methodology: 
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Synonyms: 

Quest test code 94626, Apolipoprote, ApoE3,Alzheimer's Disease (AD),ApoE4,ApoE2


Clinical significance: 

This LC-MS/MS assay identifies the ApoE isoform(s) in CSF. This information can aid in assessing likelihood of AD.


Review Date:  12/09/2024

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