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Specimen Collection Manual and Test Catalog

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BARBITURATES, CONFIRMATION BY GCMS, SERUM

Geisinger Epic Procedure Code:  LAB1124    Geisinger Epic ID:  52421

SPECIMEN COLLECTION
Specimen type: 

Serum (preferred) or plasma


Preferred collection container: 
Alternate collection container: 
3 mL lavender-top (K2 EDTA) tube
Specimen required: 

2 mL serum (preferred) or plasma: minimum 1 mL


Special notes: 

Do not collect in gel tube.



SPECIMEN PROCESSING
Processing instructions: 

Centrifuge and aliquot.


Transport temperature: 

Refrigerated (cold packs)


Specimen stability: 

Room temperature: 72 hours. Refrigerated: 7 days. Frozen: 14 days.


Rejection criteria: 

Serum separator tube (SST).



TEST DETAILS
CPT code(s):  80345
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Amobarbital, Butabarbital, Butalbital, Pentobarbital, Phenobarbital, Secobarbital


Methodology: 
Chromatography/Mass Spectrometry
Synonyms: 

Quest test code 4082, BarbConf Ser


Clinical significance: 

Extensively used for hypnotics, sedatives, and anesthetics. Readily absorbed from stomach. Duration of action of Barbiturates in therapeutic doses varies from: 8-16 hours (long acting e.g., Phenobarbital); 4-8 hours (intermediate acting e.g., Amobarbital); 3-6 hours (short acting e.g., Pentobarbital). Barbiturates may enhance other CNS depressants, such as Ethanol, Morphine derivatives, tranquilizers, and Resperine.


Review Date:  12/09/2024

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