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Specimen Collection Manual and Test Catalog

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HISTAMINE, 24-HOUR URINE

Geisinger Epic Procedure Code:  LAB1141    Geisinger Epic ID:  52489

SPECIMEN COLLECTION
Specimen type: 

Preserved 24-hour urine


Preferred collection container: 
Specimen required: 

4 mL aliquot of 24-hour urine; minimum 2 mL.


Special notes: 

Collect a 24 hour urine specimen with 10 mL of 6N HCl as a preservative.


Patient preparation: 

Avoid direct sunlight. Avoid taking allergy causing drugs, antihistamines, oral corticosteroids, and substances which block H2 receptors for at least 24 hours before specimen collection.



SPECIMEN PROCESSING
Transport temperature: 

Refrigerated (cold packs).


Specimen stability: 

Room temperature: 48 hours. Refrigerated: 14 days. Frozen: 14 days.



TEST DETAILS
Additional information: 

This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.


CPT code(s):  83088
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

24-hour urine histamine and creatinine.


Methodology: 
Immunoassay
Synonyms: 

Quest test code 15869, Histamine24


Clinical significance: 

Histamine is a mediator of the allergic response. Histamine release causes itching, flushing, hives, vomiting, syncope, and even shock. In addition, some patients with gastric carcinoids may exhibit high concentrations of histamine.


Review Date:  12/12/2024

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