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Specimen Collection Manual and Test Catalog

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HISTOPLASMA ANTIBODY PANEL, CF AND ID, SERUM

Geisinger Epic Procedure Code:  LAB1157    Geisinger Epic ID:  52553

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
6 mL red-top (plain, non-serum separator) tube
Specimen required: 

1 mL serum; minimum 0.5 mL



SPECIMEN PROCESSING
Processing instructions: 

Centrifuge and aliquot.


Transport temperature: 

Room temperature.


Specimen stability: 

Room temperature: 7 days. Refrigerated: 14 days. Frozen: 30 days.


Rejection criteria: 

Gross hemolysis, grossly lipemic, grossly icteric.



TEST DETAILS
Additional information: 

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.


CPT code(s):  86698 (x3)
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Histoplasma Antibody, Immunodiffusion, Serum, and Histoplasma Antibody, Complement Fixation, Serum.


Methodology: 
Complement Fixation
Immunodiffusion
Synonyms: 

Quest test code 37094, Histo AB


Clinical significance: 

Histoplasmosis, caused by infection by H. capsulatum, is usually asymptomatic or mild. Some patients develop chronic pulmonary histoplasmosis or acute disseminated histoplasmosis that is often life-threatening. Immunodiffusion testing detects antibodies in approximately 70% of patients with histoplasmosis, and complement fixation testing detects antibodies in approximately 90% of patients.


Review Date:  12/12/2024

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