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Specimen Collection Manual and Test Catalog

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LEUKOTRIENE E4, RANDOM, URINE

Geisinger Epic Procedure Code:  LAB1167    Geisinger Epic ID:  52593

SPECIMEN COLLECTION
Specimen type: 

Random urine


Preferred collection container: 
Specimen required: 

5 mL random urine collected in a plastic sterile vial - no preservative; minimum 2 mL.


Special notes: 

1. Collect a random urine specimen
2. No preservative



SPECIMEN PROCESSING
Processing instructions: 

Aliquot 5mL urine. Freeze upon receipt of sample.


Transport temperature: 

Frozen.


Specimen stability: 

Room temperature: 24 hours. Refrigerated: 7 days. Frozen: 28 days



TEST DETAILS
Additional information: 

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.


CPT code(s):  82542, 82570
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Methodology: 
Enzymatic Colorimetric
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Synonyms: 

Quest test code 11985, LTE4, Cysteinyl Leukotriene, Mastocytosis, Systemic Mast Cell Activation, Mast Cell Activation Syndrome


Clinical significance: 

Leukotriene E4, Random, Urine - An aid to evaluate patients suspected of having systemic mastocytosis using random urine collections.


Doctoral Director(s): 
Randin Nelson MD
Review Date:  01/27/2026

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