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Specimen Collection Manual and Test Catalog

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SENSORIMOTOR NEUROPATHY PROFILE W/ RECOMBX(R)-COMP

Geisinger Epic Procedure Code:  LAB3046    Geisinger Epic ID:  19789
Test Restriction:  ORDER LIMITED TO GENETICS AND NEUROLOGY

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Specimen required: 

2 mL aliquot of serum; minimum 0.5 mL



SPECIMEN PROCESSING
Processing instructions: 

Allow to clot. Centrifuge 10 minutes at 3000 rpm.


Transport temperature: 

Refrigerated.


Specimen stability: 

Room temperature: 72 hours. Refrigerated: 21 days. Frozen: 28 days.


Rejection criteria: 

Hemolysis, icterus, lipemia.



TEST DETAILS
Reference interval: 

Please refer to individual test components.


CPT code(s):  83520 x10
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Co-GM1 Autoantibody Test Co-Asialo-GM1 Autoantibody Test Co-GD1b Autoantibody Test GD1a Autoantibody Test GALOP Autoantibody Test SGPG Autoantibody Test MAG Autoantibody Test Recombx® Hu Autoantibody Test Sulfatide Autoantibody Test


Methodology: 
Automated Nanoliter Scale Immunoassay
Enzyme-Linked Immunosorbent Assay (ELISA)
Western Blot
Synonyms: 

SMN, ANNA-1, Quest test code 94604


Clinical significance: 

Anti-MAG, anti-SGPG, anti-GM1, anti-GD1a, anti-GD1b, anti-asialo GM1, anti-sulfatide, anti-Hu, and IgM GALOP antibodies are found in patients with a peripheral neuropathy and mixed sensory and motor symptoms. This semi-quantitative assay may be useful in monitoring therapeutic responses in select cases.


Review Date:  11/13/2024

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