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Specimen Collection Manual and Test Catalog

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TSH WITH HAMA TREATMENT

Geisinger Epic Procedure Code:  LAB1268    Geisinger Epic ID:  52997

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
6 mL red-top (plain, non-serum separator) tube
Specimen required: 

2 mL serum; Minimum: 1.5 mL.


Special notes: 

Sample may be drawn in an SST glass tube, but not submitted in this tube.


Patient preparation: 

Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks. According to the assay manufacturer Siemens: "Samples containing fluorescein can produce falsely depressed values when tested with the Advia Centaur TSH3 Ultra assay.



SPECIMEN PROCESSING
Processing instructions: 

Centrifuge and aliquot. Transfer to plastic screw-cap vial.


Transport temperature: 

Room temperature.


Specimen stability: 

Room temperature: 7 days. Refrigerated: 7 days. Frozen: 28 days.



TEST DETAILS
CPT code(s):  84443 x2
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Ultrasensitive TSH with and without HAMA treatment


Methodology: 
Immunoassay
Synonyms: 

Quest test code 19537, TSH with HAM


Clinical significance: 

Precision in the estimation of TSH is crucial to the follow-up of subjects with thyroid disorders. The preincubation of samples to remove HAMA immunoglobulins provides a way to ensure that an otherwise unsuspected rise or drop in TSH concentration will not be interpreted as either a false positive or false negative.


Review Date:  12/11/2024

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