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Specimen Collection Manual and Test Catalog

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ANTI-U3 RNP AB (FIBRILLARIN)

Geisinger Epic Procedure Code:  LAB1323    Geisinger Epic ID:  53217

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
6 mL red-top (plain, non-serum separator) tube
Specimen required: 

1 mL serum; minimum 0.5 mL.



SPECIMEN PROCESSING
Processing instructions: 

Centrifuge and aliquot.


Transport temperature: 

Refrigerated.


Specimen stability: 

Room temperature: 48 hours. Refrigerated: 14 days. Frozen: 30 days.



TEST DETAILS
CPT code(s):  86235
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Methodology: 
Radioimmunopreciptation assay (RIPA)
Synonyms: 

Quest test code 34262, Anti-U3 RNP


Clinical significance: 

The U3-RNP (Fibrillarin) particle is thought to participate in the first step of pre-ribosomal RNA processing. Anti-U3 RNP antibodies have been shown to be highly specific for patients with SSc


Review Date:  12/11/2024

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