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Specimen Collection Manual and Test Catalog

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DOUBLE STRANDED DNA (DSDNA) ANTIBODY, QUANT

Geisinger Epic Procedure Code:  LAB4298    Geisinger Epic ID:  179624

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Specimen required: 

0.5 mL serum; minimum 0.2 mL



SPECIMEN PROCESSING
Processing instructions: 

Allow to clot. Centrifuge and submit 0.5 mL serum.


Transport temperature: 

Refrigerated (preferred). Room temperature (stable 8 hours) or frozen specimen also acceptable.


Specimen stability: 

Room temperature: 8 hours. Refrigerated (2-8°C): 2 weeks. Frozen: 6 months.



TEST DETAILS
Reference interval: 

Negative <20 IU/mL


Interpretation guide: 

Negative: <20 IU/mL 
Equivocal: 20-45 IU/mL 
Positive: >45 IU/mL


CPT code(s):  86225
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Methodology: 
Enzyme Immunoassay (EIA)
Synonyms: 

DSDNA


Clinical significance: 

The presence of dsDNA antibodies in correlation with clinical findings can aid in the diagnosis of systemic lupus erythematosus.


Doctoral Director(s): 
Benjamin Andress, PhD, DABCC
Hoi-Ying Elsie Yu, PhD, DABCC, FADLM
Review Date:  01/14/2025

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