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Specimen Collection Manual and Test Catalog

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ALLERGEN NUT IGE PROFILE WITH REFLEX COMPONENT

Geisinger Epic Procedure Code:  LAB4360    Geisinger Epic ID:  180307

SPECIMEN COLLECTION
Specimen type: 

Serum


Preferred collection container: 
Alternate collection container: 
6 mL red-top (plain, non-serum separator) tube
Specimen required: 

One (1) full 3.5 mL gold-top serum separator tube; minimum 2.2 mL serum required.



SPECIMEN PROCESSING
Processing instructions: 

Allow to clot. Centrifuge and submit one (1) full 3.5 mL gold-top serum separator tube.


Transport temperature: 

Refrigerated.


Specimen stability: 

Refrigerated (2-8°C): Seven (7) days. Frozen (-20°C): Six (6) months.


Rejection criteria: 

Specimen will be rejected if stability limit has been exceeded or if specimen is hemolyzed, lipemic or icteric.



TEST DETAILS
Reference interval: 

Negative/Class 0


Interpretation guide: 

<0.10 kUa/L - Class 0 Allergen: Absence of Allergen Specific IgE 
0.10-0.34 kUa/L - Class 0/1 Allergen: Low Level of Allergen Specific IgE 
0.35-0.69 kUa/L - Class 1 Allergen: Low Level of Allergen Specific IgE
0.70-3.49 kUa/L - Class 2 Allergen: Moderate Level of Allergen Specific IgE
3.50-17.49 kUa/L - Class 3 Allergen: High Level of Allergen Specific IgE
17.5-49.99 kUa/L - Class 4 Allergen: Very High Level of Allergen Specific IgE
50.0-99.99 kUa/L - Class 5 Allergen: Very High Level of Allergen Specific IgE
>=100 kUa/L - Class 6 Allergen: Very High Level of Allergen Specific IgE


Additional information: 

Geisinger Allergy Panels.


CPT code(s):  86003 x9, 86008 x14
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.
The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.

Test includes: 

Peanut (f13) LAB1661, Hazelnut (f17) LAB1625, Brazil Nut (f18) LAB1566, Almond (f20) LAB1553, Pecan Nut (f201) LAB1663, Cashew Nut (f202) LAB1573, Walnut (f256) LAB1694, Pistachio (f203) LAB1668, Macadamia Nut (Rf345) LAB3560.

If Peanut IgE is positive, reflexes to Peanut component panel (LAB3209).
If Hazelnut IgE is positive, reflexes to Hazelnut Component Panel (LAB3867).
If Brazil Nut IgE is positive, reflexes to Brazil Nut Component Panel (LAB4349).
If Cashew Nut IgE is positive, reflexes to Cashew Component (LAB4350).
If Walnut IgE is positive, reflexes to Walnut Component Panel (LAB4351).
All reflex tests will go to Quest reference laboratory.


Methodology: 
Enzyme Immunoassay (EIA)
Synonyms: 

Nut IgE, Nut Panel, Allergy


Clinical significance: 

Many allergies are mediated by immunoglobulins of the IgE class. In vitro allergen-specific IgE tests can help the physician identify the allergen (or allergens) to which an individual is sensitive.


Doctoral Director(s): 
Benjamin Andress, PhD, DABCC
Hoi-Ying Elsie Yu, PhD, DABCC, FADLM
Review Date:  12/12/2024

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